Different antigen expression on Wolffian and Müllerian cells in rat embryos as detected by monoclonal antibodies

The Wolffian duct and the developing Müllerian duct of 14 and 15 day old rat embryos were examined with the monoclonal antibodies GZ1 and GZ2. These antibodies react with antigens situated in the cell membrane of Wolffian cells; they do not react with Müllerian cells. This different antigen expression confirms the current opinion that these cells are of different types. A cellular contribution from the Wolffian duct to the developing Müllerian duct was not found.