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Updated: Jan 24, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
The association between feeding protocol compliance and weight gain following high-risk neonatal cardiac surgery
Jamie M Furlong-Dillard1, Benjamin J Miller2, Kathy A Sward2
1Division of Critical Care, Department of Pediatrics,University of Louisville, Norton Children's Hospital, Louisville, KY,USA.
Insights
High-risk feeding protocol adherence in children with congenital heart disease improves weight gain. Focusing on adherence, not just nutrition delivery, is key for better outcomes.
Area of Science:
- Pediatric Cardiology
- Clinical Nutrition
- Health Outcomes Research
Background:
- Children with congenital heart disease (CHD) face significant malnutrition risks.
- Standardized feeding protocols show potential in mitigating these risks.
- Variability in institutional protocols and lack of adherence data necessitate analysis of protocol components.
Purpose of the Study:
- To analyze the efficacy of adherence to and deviation from feeding protocols in high-risk CHD patients.
- To assess the association between protocol adherence/deviation and clinical outcomes.
- To determine the impact on weight-for-age z-score changes.
Main Methods:
- Retrospective analysis of feeding protocol adherence and deviation in high-risk CHD patients (December 2015 - March 2017).
- Evaluation of associations between adherence/deviation and clinical outcomes.
- Primary outcome: change in weight-for-age z-score.
Main Results:
- Increased adherence and decreased deviation from feeding protocol instructions significantly improved weight-for-age z-score changes from birth to discharge (p = 0.031).
- No statistically significant differences in secondary outcomes (clinical severity markers, nutritional delivery) were observed between high and low adherence/deviation groups.
- Weight gain was linked to adherence irrespective of nutritional delivery or caloric intake.
Conclusions:
- Feeding protocol adherence in high-risk CHD patients is associated with improved weight gain.
- Protocol efficacy assessment should extend beyond caloric delivery and illness severity to include adherence measures.
- Future research should incorporate adherence and deviation metrics for comprehensive feeding protocol evaluation.
Background:
Children with congenital heart disease are at high risk for malnutrition. Standardisation of feeding protocols has shown promise in decreasing some of this risk. With little standardisation between institutions' feeding protocols and no understanding of protocol adherence, it is important to analyse the efficacy of individual aspects of the protocols.
Methods:
Adherence to and deviation from a feeding protocol in high-risk congenital heart disease patients between December 2015 and March 2017 were analysed. Associations between adherence to and deviation from the protocol and clinical outcomes were also assessed. The primary outcome was change in weight-for-age z score between time intervals.
Results:
Increased adherence to and decreased deviation from individual instructions of a feeding protocol improves patients change in weight-for-age z score between birth and hospital discharge (p = 0.031). Secondary outcomes such as markers of clinical severity and nutritional delivery were not statistically different between groups with high or low adherence or deviation rates.
Conclusions:
High-risk feeding protocol adherence and fewer deviations are associated with weight gain independent of their influence on nutritional delivery and caloric intake. Future studies assessing the efficacy of feeding protocols should include the measures of adherence and deviations that are not merely limited to caloric delivery and illness severity.
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