Measuring cognitive performance in way that incorporates the concept of active and healthy ageing (AHA)
Petra Stute1, Mélanie von Bergen2, Norman Bitterlich3
1Department of Obstetrics and Gynecology, Inselspital Bern, Switzerland.
Objectives:
To demonstrate that the mental-cognitive domain of the validated generic bio-functional status (BFS)/bio-functional age (BFA) assessment tool reflects cognitive performance, and so meets the needs of the European Innovation Partnership on Active and Healthy Ageing (EIP-AHA).
Study Design:
Monocenter, cross-sectional, observational, non-interventional trial (Bern Cohort Study 2014, BeCS-14) (Cantonal Ethics Committee, KEK-BE 023112).
Main Outcome Measures:
Ratings on the mental-cognitive BFS domain and on a validated cognitive performance test battery (Inventar der Gedächtnisdiagnostik; IGD) in 47 healthy, educated, middle-class, midlife men and women.
Results:
Mean cognitive performance was average in younger, and higher in better-educated individuals. Participants' BFA was 8.9 ± 6.6 year-equivalents below their chronological age. Subjects who performed better in the IGD (sub)domains also performed better in the BFS cognitive-mental function subdomain. Correlation analysis of the ratings in the BFS cognitive-mental function subdomain and total score on the IGD revealed that the highest correlations were achieved by the BFS parameters cognitive switching capability (r=-0.56, p < 0.001), strategic thinking (r=-0.49, p < 0.001), changeover capability (r=-0.50, p < 0.001) and stepping-stone-maze test (r=-0.51, p < 0.001).
Conclusions:
Ratings on the BFS cognitive-mental function subdomain correlated well with scores on a validated questionnaire for cognition assessment, the IGD. Therefore, the BFS/BFA assessment tool meets the needs of the EIP-AHA.
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