Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

¹H NMR: Interpreting Distorted and Overlapping Signals01:02

¹H NMR: Interpreting Distorted and Overlapping Signals

1.5K
Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are...
1.5K
Concentration Cells02:41

Concentration Cells

25.6K
A concentration cell is a type of a  voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species.
Consider the following voltaic cell:
25.6K
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

3.1K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
3.1K
Structural Protein Function01:56

Structural Protein Function

29.8K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
29.8K
Actin Polymerization01:42

Actin Polymerization

8.4K
Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶  nucleation, elongation, and steady-state phase.
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight...
8.4K
Solution Concentration and Dilution02:59

Solution Concentration and Dilution

128.2K
The relative amount of a given solution component is known as its concentration. Often, though not always, a solution contains one component with a concentration that is significantly greater than that of all other components. This component is called the solvent and may be viewed as the medium in which the other components are dispersed or dissolved. Solutions in which water is the solvent are, of course, very common on our planet. A solution in which water is the solvent is called an aqueous...
128.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Volatile Organic Compounds and Carbonyl Compounds Present in the Cabins of Newly Produced, Medium- and Large-Size Coaches in China.

International journal of environmental research and public health·2016
Same author

[Comparison and optimization of total ionic strength adjustment buffer during detecting fluoride in trace serum sample by fluoride ion selective electrode method].

Wei sheng yan jiu = Journal of hygiene research·2016
Same author

Flexible Transparent Electronic Gas Sensors.

Small (Weinheim an der Bergstrasse, Germany)·2016
Same author

Magnetoresistance in Co/2D MoS2/Co and Ni/2D MoS2/Ni junctions.

Physical chemistry chemical physics : PCCP·2016
Same author

Development and Validation of an Interactive Efficient Dose Rates Distribution Calculation Program Arshield for Visualization of Radiation Field in Nuclear Power Plants.

Radiation protection dosimetry·2016
Same author

[Effects of land use change on landscape pattern vulnerability in Yinchuan Basin, Northwest China].

Ying yong sheng tai xue bao = The journal of applied ecology·2016

Related Experiment Video

Updated: Jan 24, 2026

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
12:54

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Published on: February 12, 2013

12.9K

Structural Changes in Polymeric Gel Scaffolds Around the Overlap Concentration.

Han Zhang1, Matthew D Wehrman1, Kelly M Schultz1

  • 1Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA, United States.

Frontiers in Chemistry
|May 29, 2019
PubMed
Summary

Polymeric gel scaffolds exhibit tunable properties based on polymer concentration, impacting their structure and energy storage capabilities for diverse applications like wound healing and oil recovery.

Keywords:
hydrogel scaffoldsmultiple particle tracking microrheologyphotopolymerizationpoly(ethylene glycol)time-cure superposition

More Related Videos

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.9K
Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration
11:43

Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration

Published on: April 3, 2015

8.9K

Related Experiment Videos

Last Updated: Jan 24, 2026

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
12:54

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Published on: February 12, 2013

12.9K
Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.9K
Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration
11:43

Concentric Gel System to Study the Biophysical Role of Matrix Microenvironment on 3D Cell Migration

Published on: April 3, 2015

8.9K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Rheology

Background:

  • Cross-linked polymeric gels are vital in applications from wound healing to oil recovery.
  • Understanding structure-property relationships is key for designing these materials.
  • Polymer concentration influences physical interactions and material structure.

Purpose of the Study:

  • To characterize the gelation and structural properties of poly(ethylene glycol) (PEG)-acrylate scaffolds.
  • To investigate the impact of polymer concentration, particularly around the overlap concentration, on scaffold properties.
  • To determine the critical relaxation exponent (n) as a measure of scaffold structure and rheological behavior.

Main Methods:

  • Utilized multiple particle tracking microrheology (MPT) to monitor scaffold gelation.
  • Employed fluorescently labeled probe particles to track Brownian motion via video microscopy.
  • Applied time-cure superposition (TCS) to determine the critical relaxation exponent (n).

Main Results:

  • Below the overlap concentration, scaffolds showed a tightly cross-linked network (n = 0.40 ± 0.03), storing and dissipating energy.
  • Above the overlap concentration, a step change to a more tightly cross-linked network (n = 0.20 ± 0.03) was observed, primarily storing energy.
  • Increasing concentration beyond the overlap concentration did not alter scaffold structure.

Conclusions:

  • Scaffold properties can be tuned by adjusting polymer concentration above and below the overlap concentration.
  • The fundamental scaffold architecture remains consistent within each concentration regime.
  • This tunability is advantageous for applications requiring variable stiffness with a consistent structure.