Is transcutaneous electrical muscle stimulation an alternative for preventing acquired muscle weakness in the pediatric intensive care unit? A scoping review
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Updated: Jan 24, 2026

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Published on: September 6, 2024
Paulo Magalhães1,2, Bárbara Bernardo Figueirêdo1, Alanna Vasconcelos1
1Department of Physical Therapy, Pernambuco University, Petrolina, Pernambuco, Brazil.
Insights
Transcutaneous electrical muscle stimulation (TEMS) shows promise for pediatric intensive care unit acquired weakness (PICUAW). This review highlights its effectiveness in children with neurological disorders, suggesting potential for broader application with further research.
Area of Science:
- Pediatric intensive care
- Rehabilitation medicine
- Neurology
Background:
- Transcutaneous electrical muscle stimulation (TEMS) is used in adults to prevent muscle atrophy in intensive care units (ICUs).
- Limited research exists on TEMS application in pediatric ICUs.
- A scoping review was conducted to identify research gaps and inform future studies.
Purpose of the Study:
- To review current applications of TEMS for pediatric intensive care unit acquired weakness (PICUAW).
Main Methods:
- A literature search of online databases was performed for studies published between 2006 and 2016.
- Selected studies included participants under 18 years old and focused on musculoskeletal or cardiorespiratory outcomes.
- The review synthesized findings from six clinical trials involving 218 pediatric outpatients.
Main Results:
- TEMS protocols varied in intensity and duration, with a trend towards high intensity and short duration.
- The primary application of TEMS was in pediatric neurological disorders.
- TEMS demonstrated effectiveness in improving spasticity, bone mineral density, disability, and gait compared to sham interventions. One study showed improved VO2 with combined TEMS and cycling for spine injury.
Conclusions:
- TEMS is effective and safe for addressing musculoskeletal and cardiorespiratory impairments in children with neurological disorders.
- Individualized TEMS protocols may help prevent PICUAW, despite differing pathophysiology in outpatients.
- Further research is necessary to confirm the effectiveness of TEMS for PICUAW.
Background:
Transcutaneous electrical muscle stimulation (TEMS) has been progressively used as add-on therapy to reduce muscle atrophy in adults unable to carry out active mobilization in the intensive care unit (ICU). There are no studies addressing TEMS in the pediatric ICU. Therefore, we decided to develop a scoping review, a type of knowledge synthesis, which unlike systematic review, identify gaps in the literature to aid the planning and commissioning of future research.
Objective:
To provide current perspectives on the application of TEMS for combating pediatric intensive care unit acquired weakness (PICUAW).
Methods:
Online databases were used to identify papers published 2006-2016, from which we selected those used musculoskeletal and cardiorespiratory performance as a primary or secondary outcome variable in participants under 18 years.
Results:
The publications reported six clinical trials from 218 outpatients with 9.5 ± 8 years old. There were differences in current modulation and duration of TEMS sessions, with a predominance of high intensity and short duration in which a muscle contraction is triggered. The main use of TEMS was in pediatric neurological disorders. TEMS was more effective when compared with SHAM on spasticity, bone mineral density, disability, and gait. One study regarding spine injury showed improvement in VO2 (P = 0.035) when combined cycling with TEMS.
Conclusion:
TEMS was an effective and safe treatment for musculoskeletal impairments and cardiorespiratory performance in children with neurological disorders. Although the physiopathology is different in outpatients, an individualized protocol with TEMS might be promising for preventing PICUAW. Its effectiveness, however, deserves further investigation.
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