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Characterization of teaghrelin-like compounds from tea cultivars
Ping-Chung Kuo1, Yue-Chiun Li2, Ruo-Hsuan Wu2
1School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Abstract:
Teaghrelins, identified originally in Chin-shin oolong tea, are unique acylated flavonoid tetraglycosides and proposed to be potential oral analogues of ghrelin. In the present study, two new teaghrelin-like compounds were characterized from tea cultivars (TTES No. 12), and their chemical structures were established by the spectroscopic and spectrometric analysis. However, due to the different location of rhamnose, these two teaghrelin-like compounds may not show significant ghrelin receptor affinity.[Figure: see text].
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