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Related Experiment Videos

Is screening for bacteriuria in pregnancy worth while?

M Campbell-Brown, I R McFadyen, D V Seal

    British Medical Journal (Clinical Research Ed.)
    |June 20, 1987
    PubMed
    Summary
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    Screening pregnant women for bacteriuria (bacteria in urine) and treating it with antibiotics appears to prevent few overt urinary tract infections. The cost-effectiveness of such programs depends on local bacteriuria prevalence and progression rates.

    Area of Science:

    • Obstetrics and Gynecology
    • Urology
    • Infectious Diseases

    Background:

    • Bacteriuria in pregnancy is a known risk factor for overt urinary tract infections.
    • Screening and antibiotic treatment are common interventions, but their cost-effectiveness requires evaluation.

    Purpose of the Study:

    • To assess the prevalence of bacteriuria in pregnant women.
    • To determine the effectiveness of antibiotic treatment in preventing overt urinary tract infections.
    • To evaluate the cost-effectiveness of screening and treatment programs.

    Main Methods:

    • Dipslide screening of 4470 pregnant women for bacteriuria.
    • Re-examination of positive cases using suprapubic aspiration, catheterization, or midstream urine samples.
    • Prospective follow-up of patients with and without bacteriuria, with and without antibiotic treatment, to monitor for overt infections.

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    Main Results:

    • Significant bacteriuria was found in 5.1% of screened women.
    • Confirmed bacteriuria prevalence was 2.6%.
    • Antibiotic treatment appeared to prevent only six cases of overt infection among the studied population.

    Conclusions:

    • The screening and treatment program showed limited success in preventing overt urinary tract infections.
    • The cost-effectiveness of such interventions is contingent upon local bacteriuria prevalence and the rate of progression to overt infection.