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Updated: Jan 24, 2026

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
Published on: November 13, 2016
Hormonal and metabolic substrate status in response to exercise in men of different phenotype
J Chycki1, A Zajac1, M Michalczyk2
1Department of Sports Training, The Jerzy Kukuczka Academy of Physical Education in Katowice, Katowice, Poland.
Objectives:
The present study verified the effect of moderate-to-high-intensity aerobic exercise on the endocrine response profile and adipose tissue in young healthy men with different phenotype characteristics.
Design:
Eighteen men were divided into three experimental groups with defined body components and specific physical fitness: Endurance phenotype - EP (n = 6; low body mass; low fat content; aerobic endurance trained), Athletic phenotype - AP (n = 6; high body mass; low fat content, resistance trained), Obesity phenotype - OP (n = 6; high body mass; high fat content, untrained).
Methods:
The participants performed an progressive exercise protocol on a treadmill (30% VO2max, 50% VO2max, 70% VO2max), separated by 45 s of passive rest for blood collection.
Results:
Plasma glucose oxidation increased in relation to exercise intensity, but to a greater extent in the AP group. The free fatty acids' plasma level decreased with a rise in exercise intensity, but with different kinetics in particular phenotypes. Plasma growth hormone increased after the cessation of exercise and was significantly higher in all groups 45 min into recovery compared to resting values. Plasma insulin decreased during exercise in all groups, but in the OP, the decrease was blunted.
Conclusions:
The results indicate that the rate of lipolysis, hormonal and metabolic response to aerobic exercise depends on the individuals' phenotype. Thus, exercise type, duration and intensity have to be strictly individualized in relation to phenotype in order to reach optimal metabolic benefits.
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