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Related Concept Videos

Functions of Connective Tissues01:17

Functions of Connective Tissues

14.9K
Connective tissues perform a broad range of functions in the body. Their primary function is to connect and link different tissues in the body and act as packaging material between tissues. The areolar tissue, a connective tissue prototype, commonly cements various tissue types in diverse body organs. In contrast, adipose tissue cushions internal organs while insulating the body from heat loss.
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
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Loose Connective Tissue01:26

Loose Connective Tissue

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Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...
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Introduction to Connective Tissues01:11

Introduction to Connective Tissues

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Connective tissues are one of the four main tissue types in humans that are extensively present in the body. They are characterized by cells embedded in an extracellular matrix (ECM) composed of a ground substance and three main types of protein fibers— collagen, elastic, and reticular fibers. The ground substance of connective tissues can range from a watery and jelly-like consistency to mineralized and hard. The wide variety of cells in the connective tissues include fibroblasts,...
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Classification of Connective Tissues01:30

Classification of Connective Tissues

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The connective tissues have different properties and functions in the human body. They are broadly categorized into proper, supporting, or fluid connective tissues.
Connective Tissue Proper
Connective tissue proper is the most abundant class of connective tissues. As its name implies, it predominantly connects different tissues in the body. Depending on the cell types, ground substance, viscosity, and fiber types in the ECM, connective tissue proper is further categorized into loose and dense....
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Embryonic Connective Tissues01:20

Embryonic Connective Tissues

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During early development, the embryo forms two types of connective tissues— the mesenchyme and mucoid connective tissue.
The mesenchyme is the first connective tissue that emerges in the developing embryo. It consists of loosely arranged multipotent mesenchymal cells and reticular fibers in the extracellular matrix. This loose arrangement allows easy migration of cells, which is essential for germ layer positioning, patterning, and organ morphogenesis during embryonic development.
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Dense Connective Tissue01:13

Dense Connective Tissue

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Dense connective tissue contains more collagen fibers than loose connective tissue. As a consequence, it displays greater resistance to stretching. There are two major categories of dense connective tissue— regular and irregular.
Dense Regular Connective Tissue
In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...
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3D Printing of Preclinical X-ray Computed Tomographic Data Sets
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Computed Tomographic Imaging in Connective Tissue Diseases.

Joseph Barnett1, Anand Devaraj1

  • 1Department of Radiology, Royal Brompton Hospital, London, United Kingdom.

Seminars in Respiratory and Critical Care Medicine
|May 29, 2019
PubMed
Summary
This summary is machine-generated.

Pulmonary disease is a common complication of connective tissue diseases (CTDs). High-resolution computed tomography (HRCT) helps identify, classify, and stage lung involvement in CTDs for better patient management.

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Area of Science:

  • Radiology
  • Pulmonology
  • Rheumatology

Background:

  • Pulmonary disease is a frequent extra-articular manifestation in connective tissue diseases (CTDs).
  • Accurate assessment of lung involvement is crucial for patient prognosis and treatment strategies.
  • Radiologists play a key role in identifying and characterizing these pulmonary manifestations.

Purpose of the Study:

  • To review the high-resolution computed tomographic (HRCT) features of pulmonary involvement in CTDs.
  • To highlight the significance of these findings for reporting radiologists.
  • To aid in the classification and staging of lung disease in CTD patients.

Main Methods:

  • Review of high-resolution computed tomographic (HRCT) imaging.
  • Analysis of pulmonary features associated with various connective tissue diseases.
  • Correlation of imaging findings with clinical significance.

Main Results:

  • Detailed description of characteristic HRCT findings in different CTDs affecting the lungs.
  • Emphasis on the importance of recognizing specific patterns for diagnosis and management.
  • Significance of HRCT in differentiating various types of interstitial lung disease in CTDs.

Conclusions:

  • HRCT is essential for evaluating pulmonary manifestations of CTDs.
  • Understanding HRCT patterns aids in accurate diagnosis, staging, and prognostication.
  • This review provides a guide for radiologists reporting on CTD-related lung disease.