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Published on: December 6, 2016
[Analysis of polysomnography results between pre- and post-operation in pediatric obstructive sleep apnea hypopnea
1Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.
Insights
Adenotonsillectomy significantly improves pediatric obstructive sleep apnea hypopnea syndrome (OSAHS) by reducing respiratory events and enhancing sleep architecture. However, some children may not achieve complete relief from this surgical intervention.
Area of Science:
- Otolaryngology
- Pediatric Sleep Medicine
- Respiratory Medicine
Background:
- Pediatric obstructive sleep apnea hypopnea syndrome (OSAHS) significantly impacts children's health and development.
- Adenotonsillectomy is a common treatment, but objective data on its effectiveness are crucial.
Purpose of the Study:
- To objectively evaluate the effects of adenotonsillectomy on pediatric OSAHS using polysomnography (PSG).
- To analyze changes in respiratory events and sleep architecture post-surgery.
Main Methods:
- 56 pediatric OSAHS patients underwent pre- and post-operative PSG analysis.
- Comparison of respiratory parameters and sleep architecture using statistical tests (paired t-test, unpaired t-test, rank sum test).
Main Results:
- Adenotonsillectomy demonstrated an 85.71% short-term cure rate for pediatric OSAHS.
- Significant decreases were observed in apnea-hypopnea index (AHI), oxygen desaturation index (ODI), and arousal index.
- Improvements in sleep architecture included increased stage II and REM sleep percentages.
Conclusions:
- Pediatric OSAHS exhibits distinct respiratory event characteristics compared to adults.
- Adenotonsillectomy effectively reduces respiratory events and improves sleep architecture in most pediatric OSAHS patients.
- Complete resolution of OSAHS is not achieved in all patients following adenotonsillectomy.
Abstract:
Objective: To determine the objective effects of adenotonsillectomy on pediatric obstructive sleep apnea hypopnea syndrome (OSAHS) through analyzing the polysomnography (PSG) results between pre and post-operation. Methods: A total of 56 pediatric OSAHS patients were included who underwent adenoidectomy or/and tonsillectomy and completed PSG follow-up from January 1, 2017 to March 31, 2018. All the pediatric patients who underwent adenoidectomy or/and tonsillectomy during the research period were arranged to take a preoperative PSG study. Patients who were diagnosed OSAHS would be encouraged to complete a follow-up PSG study ranged from1 to 3 months after surgery. The parameters of respiration and sleep architecture of PSG were compared and analyzed. The paired student t test was used to compare preoperative and postoperative mean values. The unpaired student t test was used to compare quantitative variables among different groups. The rank sum test was used if the data were abnormal distribution. Results: Totally 238 patients completed preoperative PSG study, 62 patients were diagnosed as pediatric OSAHS, 56 eligible patients finished post-operative PSG. Hypopnea was the majority in all type of respiratory events in 56.45% (35/62) subjects, while central apnea as the majority in 29.03% (18/62) subjects who can also get significant CAI decrease after surgery. However, obstructive apnea as the majority only exist in 14.52% (9/62) subjects. The short-term cure rate of pediatric OSAHS was 85.71% (48/56). The postoperative AHI, MAI, CAI, HI, ODI, LoSpO(2), percentage of stage I sleep and arousal index were significantly decreased, however, the OAI was no statistical decrease. The percentage of stage Ⅱ and rapid eye movement (REM) sleep were significantly increased, while no significant change in percentage of slow wave sleep and sleep efficiency(t=2.32, P=0.017). Conclusions: Pediatric OSAHS manifest different characteristics of respiratory events from that of adults. Adenotonsillectomy can significant decrease respiratory events and improve sleep architecture, however, there are still some patients who can't be completely relieved with adenotonsillectomy.
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