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Published on: December 6, 2016
Adherence to Positive Airway Pressure for the Treatment of Obstructive Sleep Apnea in Children With Developmental
Eun Kyeong Kang1,2, Melissa S Xanthopoulos1, Ji Young Kim1,3
1Sleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Insights
Children with developmental disabilities (DD) showed better adherence to positive airway pressure (PAP) therapy, measured by nights used, compared to typically developing children. Usage duration was similar, indicating successful PAP use in children with DD.
Area of Science:
- Pediatric Sleep Medicine
- Developmental Disabilities Research
- Respiratory Therapy
Background:
- Obstructive sleep apnea (OSA) is prevalent in children.
- Positive airway pressure (PAP) therapy is a common treatment for OSA.
- Understanding adherence patterns in children with developmental disabilities (DD) is crucial for effective treatment.
Purpose of the Study:
- To compare PAP adherence between children with DD and typically developing (TD) children.
- To identify factors influencing PAP adherence in pediatric OSA patients.
Main Methods:
- Retrospective analysis of PAP adherence in 240 children with OSA.
- Comparison of adherence metrics (percentage of nights used, hours of usage) at 3 and 6 months.
- Median regression modeling to identify predictive factors of adherence.
Main Results:
- Children with DD demonstrated significantly higher percentage of nights used at 3 and 6 months compared to TD children.
- Hours of PAP usage on nights used were similar between DD and TD groups.
- Adherence improved over time in both groups; higher income and earlier titration predicted adherence.
Conclusions:
- Children with DD exhibit better PAP adherence, specifically in terms of nightly usage, than TD children.
- PAP therapy is a viable and effective treatment for OSA in children with DD.
- Socioeconomic factors and treatment initiation timing influence adherence across all children.
Study Objectives:
To determine whether adherence to positive airway pressure (PAP) differs in children with developmental disabilities (DD) compared to typically developing (TD) children.
Methods:
PAP adherence of 240 children initiated on PAP for obstructive sleep apnea (OSA) was retrospectively analyzed. Adherence between groups, expressed as percentage of nights used and hours of usage on nights used at 3 and 6 months, was compared. Predictive factors of adherence were studied using a median regression model.
Results:
A total of 103 children with DD (median [interquartile range] age = 7.9 [3.2-13.1] years) and 137 TD (11.0 [5.5-16.1], P = .005) children were included. Percentage of nights used was significantly higher in children with DD at 3 (DD = 86.7 [33.9-97.9], TD = 62.9 [30.8-87.8] P = .01) and 6 months (DD = 90.0 [53.3-100], TD = 70.7 [29.2-90.8], P = .003). Hours of usage on nights used at 3 and 6 months were similar between groups (DD = 5.0 [1.4-7.9], TD = 4.6 [1.9-7.2], P = .715; DD = 6.4 [1.8-8.3], TD = 5.7 [2.5-7.3], P = .345, respectively). This adherence measure improved over time in both groups (DD, P = .007; TD, P = .005). At 6 months, higher median neighborhood income and titration at or before 6 months were significantly predictive for percentage of nights used; higher PAP pressure was significantly predictive for hours of usage in both groups.
Conclusions:
Children with DD had better PAP adherence expressed as percentage of nights used than TD children. Hours of usage on nights used at 3 and 6 months were similar between groups and improved over time. Higher income and titration at or before 6 months were predictive of adherence in all children. These findings indicate that children with DD can successfully wear PAP.
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