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Primary mitral valve regurgitation: Update and review
Eirini Apostolidou1, Andrew D Maslow2, Athena Poppas1
1Brown University, Section of Cardiology.
Global Cardiology Science & Practice
|May 30, 2019
Summary
This review covers primary mitral regurgitation, focusing on causes, assessment, and management. It discusses new staging concepts and the debate between watchful waiting and early surgery for severe cases.
Area of Science:
- Cardiology
- Valvular Heart Disease
Background:
- Mitral regurgitation is a prevalent valvular disorder globally.
- Degenerative mitral regurgitation is a common cause requiring surgical intervention.
Purpose of the Study:
- To review the current understanding of primary, degenerative mitral regurgitation.
- To address etiology, assessment, natural history, and management strategies.
Main Methods:
- Literature review of primary, degenerative mitral regurgitation.
- Analysis of current concepts in staging and adverse predictors.
- Examination of the controversy surrounding management options.
Main Results:
- Summarizes current knowledge on mitral regurgitation etiology and progression.
- Highlights newer predictors of adverse outcomes.
- Discusses the ongoing debate on optimal timing for surgical intervention.
Conclusions:
- Provides a comprehensive overview of primary mitral regurgitation.
- Addresses emerging concepts in disease staging and management.
- Informs clinical decision-making for severe, asymptomatic mitral regurgitation.
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