Coronary angiographic findings in dilated cardiomyopathy in a sub-Saharan African population
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Published on: May 16, 2020
Roland N'Guetta1, Hermann Yao1, Esther Ehouman1
1Abidjan Heart Institute, Abidjan, Côte d'Ivoire.
Insights
Coronary angiography in sub-Saharan Africa revealed that a significant portion of dilated cardiomyopathy patients have coronary artery disease (CAD). Early assessment, especially with risk factors, can improve dilated cardiomyopathy management and outcomes.
Area of Science:
- Cardiology
- Internal Medicine
- Public Health
Background:
- Dilated cardiomyopathy (DCM) management can be complex, particularly in regions with potential underdiagnosis of contributing factors.
- Understanding the coronary angiographic profile in DCM patients is crucial for effective treatment strategies.
Purpose of the Study:
- To characterize coronary angiographic findings in patients diagnosed with dilated cardiomyopathy.
- To enhance the management of dilated cardiomyopathy in a sub-Saharan African setting.
Main Methods:
- A cross-sectional study was conducted involving 108 adult patients with DCM who underwent coronary angiography.
- Data on patient demographics, cardiovascular risk factors, and angiographic results were analyzed.
Main Results:
- Hypertension was the most prevalent cardiovascular risk factor (53.7%).
- Coronary angiography showed abnormalities in 34.3% of patients, with 21.3% having obstructive coronary artery disease (CAD).
- Hypertension and diabetes were significantly more common in patients with CAD.
Conclusions:
- Ischemic heart disease may be underdiagnosed in sub-Saharan Africa among DCM patients.
- Coronary angiography is recommended for DCM patients, particularly those with cardiovascular risk factors, to optimize management and prognosis.
Aim:
To describe the coronary angiographic aspects observed in patients with dilated cardiomyopathies (DCM) in a sub-Saharan African country in order to improve their management.
Methods:
This was a cross-sectional study conducted from 1 January 2010 to 31 March 2016. All patients aged 18 years and older, presenting with DCM and admitted to Abidjan Heart Institute, who underwent coronary angiography were included. One hundred and eight patients were selected. We analysed and compared the coronary angiographic features observed.
Results:
The median age of our patients was 52 years (46-61). There was a male predominance (sex ratio = 3). Hypertension (53.7%) was the major cardiovascular risk factor found. Coronary angiography was abnormal in 37 patients (34.3%). Twenty-three patients (21.3%) had obstructive coronary artery disease (CAD). Patients with CAD were older than those with normal coronary arteries, but with no statistically significant difference (p = 0.06). Hypertension (p < 0.001) and diabetes (p = 0.0003) were statistically significantly more commonly reported in patients with CAD.
Conclusions:
Ischaemic heart disease is likely to be underdiagnosed in sub-Saharan Africa. A coronary angiographic assessment of patients receiving treatment for DCM, especially in the presence of cardiovascular risk factors, should help optimise their management and improve prognosis.
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