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Chromium(III)-doped carbon dots: fluorometric detection of p-nitrophenol via inner filter effect quenching
Chunmei Li1, Youkun Zheng1, Hongwei Ding1
1State Key Laboratory of Bioelectronics, National Demonstration Center for Experimental Biomedical Engineering Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Abstract:
We report on the synthesis of chromium(III)-doped carbon dots (Cr-CDs) by one-pot hydrothermal pathway using tris(2, 4-pentanedionato) chromium(III) and polyethyleneimine as precursors. The Cr-CDs have a graphene-analogous structure and display blue-green fluorescence with excitation/emission maxima at 350/466 nm, a 20% quantum yield, and excitation-independent emissions. Their cytotoxicity is low. The Cr-CDs were used as a fluorescence probe for p-nitrophenol (p-NP). The assay has a linear working range that extends from 0.8~150 μM and a 0.27 μM lower detection limit. The assay was applied to the detecting of p-NP in spiked human urine, and conceivably may be extended to a method for the determination of parathion. Graphical abstract Schematic presentation for the synthesis of Cr-CDs (chromium(III)-doped carbon dots) and their application to the fluorometric determination of p-NP (p-nitrophenol) based on an inner filter effect.
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