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Updated: Jan 24, 2026

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
Published on: August 5, 2021
Is Stem Cell Commerce in Small Animal Therapies Scientifically and Morally Justified?
Luane Lopes Pinheiro1, Ana Rita de Lima2, Érika Branco2
1Institute of Animal Health and Production, Federal Rural University of Amazônia, Av. Perimetral, 2501, Belém, Pará, 66.077-830, Brazil. luanelopespinheiro@gmail.com.
Abstract:
The lack of clear regulations for the use of veterinary stem cells has triggered the commercialization of unproven experimental therapies for companion animal diseases. Adult stem cells have complex biological characteristics that are directly related to the therapeutic application, but several questions remain to be answered. In order to regulate the use of these cells, well-conducted, controlled scientific studies that generate high-quality data should be performed, in order to assess the efficacy and safety of the intended treatment. This paper discusses the scientific challenges of mesenchymal stem cell therapy in veterinary regenerative medicine, and reviews published trials of adipose-tissue-derived stem cells in companion animal diseases that spontaneously occur.
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