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Published on: May 27, 2015
A novel alkaloid glycoside isolated from Atalantia buxifolia
Hui-Xian Liang1, Jing-Jing Sun1, Zhi-Bin Shen1
1School of Traditional Chinese Medicinal Chemistry, Guangdong Pharmaceutical University, Guangzhou, China.
Abstract:
From the dried root and rhizomes of Atalantia buxifolia afford 11 compounds, one new compound 1 and ten known compounds 2-11 were isolated and identified. The novel compound 1 was alkaloid glycoside. Its mother nuclear was the acridone, which was relatively rare. The structure of compound 1 was established identified by spectrum and elucidated as β-D-Glu-4,5-dimethoxy-1,6-dihydroxy-10-methyl-acridone. The compound 1 enriched the compound library and laid the material foundation for the subsequent study of pharmacological activities.
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