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Published on: July 15, 2018
Triterpenoids from the fresh pericarps of Juglans hopeiensis
Yi Lin1, Xiaogang Peng1, Juan Chen1
1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Abstract:
Two new triterpenoids (1-2), jughopanes A (1) and jughopanes B (2), along with seventeen known ones (3-19), were isolated from the fresh pericarps of Juglans hopeiensis Hu. Their structures were settled by integrated spectroscopic techniques. All isolates were tested for their cytotoxic activities and the results showed that 7 exhibited moderate cytotoxicities against MCF7 and HT29 cancer cell lines with IC50 values of 5.24 and 6.01 μM, respectively.
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