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Experience of left atrial appendage occlusion with the WATCHMAN device in Chinese patients

Zhengqin Zhai1, Min Tang1, Xi Su2

  • 1Department of Arrhythmia, State Key Laboratory of Cardiovascular Disease, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing-China.

Anatolian Journal of Cardiology
|May 31, 2019
PubMed

Insights

Left atrial appendage occlusion (LAAO) with the WATCHMAN device is safe and effective in Chinese patients with atrial fibrillation (AF). The procedure shows a high success rate and low complication rate, with most patients receiving oral anticoagulation post-procedure.

Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Procedures

Background:

  • Atrial fibrillation (AF) is a common arrhythmia, increasing stroke risk.
  • Left atrial appendage occlusion (LAAO) is an alternative to oral anticoagulation for stroke prevention in AF patients.
  • Limited data exists on LAAO using the WATCHMAN device in the Chinese population.

Purpose of the Study:

  • To evaluate the acute procedural performance of LAAO with the WATCHMAN device in China.
  • To assess the complication rates associated with LAAO procedures in Chinese patients.
  • To analyze patient selection criteria and trends for LAAO in China.

Main Methods:

  • Retrospective analysis of 658 consecutive Chinese patients undergoing LAAO with WATCHMAN device (2014-2017).
  • Patients categorized into four groups based on the year of procedure.
  • Analysis of procedural success, complication rates, patient characteristics, selection, and management trends.

Main Results:

  • Successful LAAO implantation in 97.7% of patients (643/658).
  • Low procedural complication rate of 0.6%.
  • Increasing trends in CHA2DS2-VASc and HAS-BLED scores observed over the study period. Common indications included high bleeding risk (45.6%) and OAC non-compliance (51.4%).

Conclusions:

  • LAAO with WATCHMAN device is a successful and safe procedure in Chinese AF patients.
  • High procedural success and low complication rates were demonstrated.
  • Increased bleeding risk and OAC non-compliance are primary indications for LAAO in this population, with most patients continuing OAC post-procedure.
Abstract

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