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Effect of maternal anemia on the status of iron stores in infants: A cohort study

Arvind K Shukla1, Shitanshu Srivastava1,2, Garima Verma1

  • 1Department of Pediatrics, Era Lucknow Medical College, Lucknow, Uttar Pradesh, India.

Journal of Family & Community Medicine
|May 31, 2019
PubMed

Insights

Maternal iron deficiency anemia negatively impacts infant iron stores and hemoglobin levels at birth and 14 weeks. Early interventions are crucial for infant iron status.

Area of Science:

  • Pediatrics
  • Maternal-Fetal Medicine
  • Nutritional Science

Background:

  • Iron deficiency anemia in pregnant women poses risks to infant iron reserves.
  • Maternal anemia can lead to anemia in infants later in life.
  • Understanding the impact of maternal anemia on infant iron status is critical for early intervention.

Purpose of the Study:

  • To compare hemoglobin and iron store status in infants born to anemic versus non-anemic mothers.
  • To determine the correlation between maternal and infant iron status.
  • To assess infant iron status at birth and 14 weeks postpartum.

Main Methods:

  • A cohort study involving 180 mother-infant pairs, divided into anemic and non-anemic maternal groups.
  • Hemoglobin and ferritin levels measured in infant cord blood at birth and at 14 weeks.
  • Statistical analysis using Chi-square and t-tests to compare groups and assess correlations.

Main Results:

  • Infants of anemic mothers had significantly lower hemoglobin and ferritin levels at birth and 14 weeks compared to infants of non-anemic mothers.
  • Significant correlation observed between maternal and infant hemoglobin and ferritin levels.
  • Infant iron status at 14 weeks remained significantly lower in the group born to anemic mothers.

Conclusions:

  • Maternal iron deficiency anemia adversely affects infant iron status.
  • Infants born to anemic mothers exhibit poorer iron reserves.
  • Timely and appropriate interventions are necessary to address maternal iron deficiency and its impact on infants.
Abstract

Keywords:
Anemiahemoglobininfants

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