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Updated: Jan 24, 2026

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
Published on: October 6, 2023
Onycholysis an early indicator of thyroid disease
Malumani Malan1,2, Zhe Dai3, Wu Jianbo4
1Department of Dermatology and Venereology at Zhongnan Hospital of Wuhan University PR China.
Abstract:
Onycholysis is also referred to plummer's nails is a dermatological nail disorder characterized by spontaneous distal separation of the nail plate from the free margin and progressively proximally. We discuss a case of the 38-year-old man with onycholysis associated with hyperthyroidism due to Graves' disease. In this case review, we will discuss an association of onycholysis with thyroid disease and its diagnostic prognosis. Any unexplained onycholysis should prompt the clinician to investigate the client for asymptomatic hyperthyroidism.
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