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Effect of Celery Extract on Thyroid Function; Is Herbal Therapy Safe in Obesity?
Mohammad Bagher Maljaei1,2,3,4, Seyedeh Parisa Moosavian2,3, Omid Mirmosayyeb2,5
1Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
International Journal of Preventive Medicine
|May 31, 2019
Summary
Oral celery extract consumption for weight loss may trigger hyperthyroidism. A patient experienced symptoms after consuming celery extract, leading to a diagnosis of hyperthyroidism potentially linked to the herb.
Area of Science:
- Endocrinology
- Herbal Medicine
- Toxicology
Background:
- Celery (Apium graveolens) is widely used in traditional medicine.
- Its consumption for weight loss is a growing trend.
- Potential adverse effects of herbal remedies require investigation.
Observation:
- A 36-year-old female presented with symptoms including blurred vision, palpitations, and nausea.
- She reported consuming 8g/day of celery extract powder for weight reduction, achieving a 26kg loss over 78 days.
Findings:
- Thyroid function tests revealed suppressed serum thyroid-stimulating hormone (TSH) at 0.001 mIU/L and elevated T4 at 23 ng/dl.
- Graves' disease and thyrotoxicosis were excluded through laboratory evaluations.
- Treatment with methimazole (10 mg/day) and discontinuation of celery extract led to normalization of TSH levels.
Implications:
- This case suggests that celery extract consumption may induce hyperthyroidism, potentially as an allergic reaction or direct stimulatory effect.
- Further research is warranted to explore the mechanisms and prevalence of celery-induced hyperthyroidism.
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