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Non-functional retroperitoneal paraganglioma: A case report
Ashok K Chattoraj1, Uma M Rao1, Nilanjan Sarkar2
1Department of General Surgery, Tata Main Hospital, Jamshedpur, Jharkhand, India.
Paragangliomas are rare autonomic nervous system tumors. This case highlights how non-functional paragangliomas can be misdiagnosed as gastrointestinal stromal tumors (GISTs) before surgical removal and histopathology.
Area of Science:
- Oncology
- Pathology
- Endocrinology
Background:
- Paragangliomas are extra-adrenal tumors originating from the autonomic nervous system.
- They can occur in various locations, including the abdomen, mimicking other retroperitoneal neoplasms.
- Functional paragangliomas secrete catecholamines, causing symptoms like hypertension and palpitations.
Observation:
- A 36-year-old female presented with an abdominal mass.
- The initial clinical diagnosis was gastrointestinal stromal tumor (GIST).
- The patient underwent surgical excision of the mass.
Findings:
- Postoperative histopathological examination revealed the mass to be a paraganglioma.
- Non-functional paragangliomas can present without catecholamine excess symptoms.
- This can lead to misdiagnosis, potentially being mistaken for GISTs.
Implications:
- Accurate preoperative diagnosis of retroperitoneal tumors is crucial.
- Histopathological examination is essential for definitive diagnosis.
- Awareness of paraganglioma's potential to mimic GISTs is important for clinicians.
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