Related Experiment Video
Updated: Jan 24, 2026

Antibody Transfection into Neurons as a Tool to Study Disease Pathogenesis
Published on: September 26, 2012
Evolutionary aspects of Parvovirus B-19V associated diseases and their pathogenesis patterns with an emphasis on
Piyanki Das1, Koustav Chatterjee1, Nabanita Roy Chattopadhyay1
1Department of Biotechnology, Visva Bharati Santiniketan, Siksha Bhavana, Bolpur, West Bengal 731235 India.
Abstract:
Parvovirus B-19, a single human pathogenic member of the Parvoviridae family with it's small ssDNA and non-enveloped structure, is known to cause diseases in erythroid progenitor cells. But a wide range of clinical association of this virus with cells of non-erythroid origins has recently been discovered and many of those are being investigated for such association. Higher substitution rates in due course of evolution has been suggested for this cellular tropism and persistence. In this report, we have summarized the different disease manifestations of B-19 virus and have tried to find out a pattern of pathogenesis. Finally, we have focused on the vaccination strategies available against B-19 virus to correlate these with the mechanisms involved in various diseases caused by this virus.
Related Concept Videos
What is Evolutionary History?
Vaccinations
Evolutionary Psychology
Criticisms of the Evolutionary Perspective
Evolutionary psychology provides one explanation for these findings, suggesting...
Evolutionary Relationships through Genome Comparisons
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

