A bright red-emitting flavonoid for Al3+ detection in live cells without quenching ICT fluorescence
Chathura S Abeywickrama1, Keti A Bertman, Yi Pang
1Department of Chemistry, University of Akron, Akron, Ohio 44325, USA. yp5@uakron.edu.
Abstract:
A bright red-emitting flavonoid derivative was synthesized, which exhibited a large Stokes shift (Δλ > 150 nm) and high fluorescence quantum yields (φfl = 0.10-0.35). The probe could form a stable complex with Al3+ in 1 : 1 binding stoichiometry, generating a large bathochromic shift in both absorption and fluorescence (Δλ ≈ 70 nm) to enable ratiometric determination of cellular Al3+.
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