Related Experiment Video
Updated: Sep 13, 2026

Ovarian Tissue Culture to Visualize Phenomena in Mouse Ovary
Published on: June 19, 2018
Control of follicular growth and development
Abstract:
During folliculogenesis a group of growing preantral follicles becomes responsive and dependent upon gonadotrophins, especially FSH, for their continued growth and differentiation. However, most of these follicles undergo atresia. The mechanisms that result in survival of a specific number of ovulatory (dominant) follicles appear to depend upon: (a) responsiveness of preantral follicles to gonadotrophins, (b) inhibitory and stimulatory factors from a dominant follicle, and (c) an exquisitely sensitive long-loop feedback system between the dominant follicle and pituitary gland.
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