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Related Experiment Video

Updated: Jan 24, 2026

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model

Published on: August 29, 2013

Accelerated aging in serious mental disorders.

Francesco S Bersani^1,2, Synthia H Mellon³, Victor I Reus²

¹Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy.

Current Opinion in Psychiatry

|May 31, 2019

Summary

Serious mental disorders (SMDs) may accelerate biological aging. This suggests SMDs are whole-body conditions, not just brain disorders, impacting overall health and somatic systems.

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Area of Science:

Gerontology
Psychiatry
Biomarkers

Background:

Growing evidence links serious mental disorders (SMDs) to accelerated biological aging.
This perspective reframes SMDs as multisystemic conditions with significant physical health implications.

Purpose of the Study:

To review the concept of accelerated biological aging in SMDs.
To discuss proposed biological aging markers examined in SMDs.
To evaluate the utility of these markers in understanding and treating SMDs.

Main Methods:

Review of clinical, epidemiological, and biological evidence.
Examination of recent findings on biological aging markers in SMDs.
Synthesis of current research and future directions.

Main Results:

Reports indicate accelerated changes in aging biomarkers in individuals with SMDs.
Several biological aging markers have been investigated in the context of SMDs.

Conclusions:

Accelerated biological aging is a plausible correlate of SMDs.
Understanding these markers can enhance treatment and management of SMDs.
Further research is needed to clarify the role and implications of these markers.