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Updated: Jan 24, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
Published on: December 23, 2016
CO2 -Activated Reversible Transition between Polymersomes and Micelles with AIE Fluorescence
Dapeng Zhang1, Yujiao Fan1, Hui Chen1
1Chimie ParisTech, PSL University, CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75231, Paris, France.
Abstract:
Fluorescent polymersomes with both aggregation-induced emission (AIE) and CO2 -responsive properties were developed from amphiphilic block copolymer PEG-b-P(DEAEMA-co-TPEMA) in which the hydrophobic block was a copolymer made of tetraphenylethene functionalized methacrylate (TPEMA) and 2-(diethylamino)ethyl methacrylate (DEAEMA) with unspecified sequence arrangement. Four block copolymers with different DEAEMA/TPEMA and hydrophilic/hydrophobic ratios were synthesized, and bright AIE polymersomes were prepared by nanoprecipitation in THF/water and dioxane/water systems. Polymersomes of PEG45 -b-P(DEAEMA36 -co-TPEMA6 ) were chosen to study the CO2 -responsive property. Upon CO2 bubbling vesicles transformed to small spherical micelles, and upon Ar bubbling micelles returned to vesicles with the presence of a few intermediate morphologies. These polymersomes might have promising applications as sensors, nanoreactors, or controlled release systems.
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