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1Hochschule Ruhr West, University of Applied Sciences, Medical Informatics and Bioinformatics, 45407 Mülheim an der Ruhr, Germany.
Journal of Integrative Bioinformatics
|May 31, 2019
Summary
Big data analysis faces challenges with duplicated computational tools and untested pipelines. A new cloud-ready system is proposed to improve reliability and streamline bioinformatics workflows.
Area of Science:
- Bioinformatics and computational biology.
- Data-driven scientific research.
Background:
- Big data and complex analysis workflows are prevalent in data-driven science, particularly bioinformatics.
- Numerous computational tools exist for data analysis, leading to duplicated effort (e.g., >50 read mapping tools).
- Current workflow management systems often integrate largely untested tools, yielding unpredictable results.
Purpose of the Study:
- To address the challenges of duplicated effort and tool reliability in scientific data analysis.
- To propose a new system for managing computational pipelines that is cloud-ready.
- To facilitate development and analysis in both public and private cloud environments.
Main Methods:
- The study identifies limitations in existing workflow management systems regarding cloud transition.
- It proposes a novel system architecture designed for cloud integration.
- Key features include overcoming duplicated efforts, introducing rigorous testing, and enabling cloud-based development and analysis.
Main Results:
- Current systems are not prepared for the shift towards cloud-based data analysis.
- A significant amount of duplicated effort exists in the development of computational tools.
- The reliability of integrated tools in current pipelines is often uncertain.
Conclusions:
- A new, cloud-ready workflow management system is needed to address current inefficiencies and reliability issues.
- The proposed system aims to reduce duplicated efforts, enhance tool testing, and support cloud-based scientific analysis.
- Future development should focus on creating robust, interactive, and cloud-integrated data analysis pipelines.
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