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Updated: Jan 24, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
[Radiation-induced head and neck pain: Management with botulinum toxin a injections]
M Mailly1, S Benzakin1, A Chauvin2
1Service d'ORL et chirurgie cervico-faciale, fondation Adolphe de Rothschild, 29, rue Manin, 75019 Paris, France.
Purpose:
To report the results of Botulinum Toxin A (BTA) for radiation-induced head and neck pain.
Materials And Methods:
This single-center retrospective study included all the patients treated at our institution with botulinum toxin A injections for radiation-induced head and neck pain between 2006 and 2017. Pain was evaluated by each patient on a visual analogue scale (VAS) (between 0 and 10) before, and 1 month after the injection.
Results:
Sixteen patients were included in this series. The mean value of the pain was 8.5 before and 8 after the first injection. The difference was statistically significant (p<0.01). Major response occurred in 15 patients (VAS≤3 after BTA) and complete response in 11 patients (VAS=0 after BTA).
Conclusion:
Botulinum toxin is an effective treatment for radiation-induced head and neck pain.
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