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Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty
Published on: February 27, 2018
Conversion of Failed Hemiarthroplasty to Total Hip Arthroplasty Remains High Risk for Subsequent Complications
Nicholas M Hernandez1, Kristin M Fruth2, Dirk R Larson2
1Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Insights
Conversion from hemiarthroplasty to total hip arthroplasty (THA) has high complication rates. Cumulative incidence, accounting for death, offers a more accurate revision risk estimate than Kaplan-Meier for these complex hip surgeries.
Area of Science:
- Orthopedic Surgery
- Biostatistics
- Medical Device Outcomes
Background:
- Outcomes of converting failed hemiarthroplasty to total hip arthroplasty (THA) are sparsely documented.
- The impact of mortality on implant survivorship estimates in these cases requires further investigation.
Purpose of the Study:
- To assess risks and predictors of complications, dislocations, reoperations, and revisions after conversion THA.
- To quantify the influence of competing mortality risk on outcome evaluations in patients undergoing conversion THA.
Main Methods:
- Retrospective analysis of 389 patients undergoing conversion THA from hemiarthroplasty (1985-2014).
- Revision rates calculated using Kaplan-Meier and cumulative incidence methods, with death as a competing risk.
- Cox regression models used to identify risk factors for adverse events.
Main Results:
- Over 9.3 years follow-up: 122 complications, 34 dislocations, 69 reoperations, 51 revisions.
- Conversion for periprosthetic fractures (HR 4.30) and increasing age (HR 1.32) predicted reoperations.
- No significant improvement in complication or revision rates over 30 years.
- Kaplan-Meier overestimated revision risk by 7% (15 years) and 10% (20 years) compared to cumulative incidence.
Conclusions:
- Conversion from hemiarthroplasty to THA is associated with a high risk of subsequent complications.
- Cumulative incidence provides a more accurate assessment of revision risk in this patient cohort.
Background:
Few studies have described the outcomes following conversion of failed hemiarthroplasties to total hip arthroplasty (THA) and the impact of mortality when estimating implant survivorship. The aims of this study were to evaluate the following: (1) the risks and predictors of complications, dislocations, reoperations, and revisions and (2) the extent of competing risk of death when evaluating outcomes in patients converted from hemiarthroplasty to THA.
Methods:
The study comprised 389 patients treated with conversion THA following hemiarthroplasty for femoral neck fractures between 1985 and 2014. Revision rates were calculated using both the Kaplan-Meier method and cumulative incidence accounting for death as a competing risk. Risk factors were evaluated using Cox regression models.
Results:
During an average 9.3 years of follow-up, there were 122 complications, 34 dislocations, 69 reoperations, and 51 revisions. Conversion for periprosthetic fractures was associated with a higher risk of reoperations (hazard ratio 4.30, 95% confidence interval 1.94-9.52). Increasing age was a risk factor for reoperations (hazard ratio 1.32, 95% confidence interval 1.10-1.59). No decrease in the rate of complications, dislocations, reoperations, or revisions was observed over the entire 30 years of the study either when evaluating year of surgery as a continuous variable or when comparing specific calendar year intervals (1985-1989, 1990-1999, 2000-2009, 2010-2014) (P > .05). Compared to the cumulative incidence accounting for the competing risk of death, the Kaplan-Meier method overestimated the risk of revision by 7% at 15 years and 10% at 20 years.
Conclusion:
Conversion from hemiarthroplasty to THA remains at high risk for subsequent complications. The cumulative incidence estimate provides a more accurate estimate of revision risk.
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