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Synthesis of an Intein-mediated Artificial Protein Hydrogel
Published on: January 27, 2014
A click mediated route to a novel fluorescent pyridino-extended calix[4]pyrrole sensor: synthesis and binding studies
Ahmad Rifai1, Nancy AlHaddad, Manale Noun
1Lebanese Atomic Energy Commission, National Council for Scientific Research, B. P. 11-8281, Riad El Solh 1107, 2260 Beirut, Lebanon.
Abstract:
A novel fluorescent aryl-extended phenoxycalix[4]pyrrole ditopic sensor with enhanced cation recognition properties was efficiently synthesized via click chemistry and characterized through both molecular fluorescence and nuclear magnetic resonance spectroscopy. Results demonstrate the selectivity of this fluorescent sensor for fluoride when taking into account its interaction with anions, while its cation binding properties showed selectivity for iron, and its sensing properties for several cations in dimethylsulfoxide. This work introduces a new ditopic receptor able to complex major environmentally relevant species and depicts the importance of click chemistry in the introduction of new tetra-chromophoric calix[4]pyrrole binding platforms with specific photophysical properties.
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