Related Experiment Video
Updated: Jan 24, 2026

A 96 Well Microtiter Plate-based Method for Monitoring Formation and Antifungal Susceptibility Testing of Candida albicans Biofilms
Published on: October 21, 2010
In vitro lytic activity and antifungal susceptibility of infrequently isolated yeasts
Alexandra M Montoya1, Carolina E Luna-Rodríguez1, Gabriela Gracia-Robles1
1Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Ave. Francisco I. Madero s/n, 64460, Monterrey, Mexico.
Abstract:
Non-albicans Candida species have acquired relevance in the last decades as a cause of serious disease. The virulence factors and antifungal susceptibility of these rare pathogens remain largely unrecognized. We examined a total of 50 yeast isolates corresponding to 11 different infrequently isolated yeast species for their in vitro enzymatic profile and susceptibility pattern as first-line antifungals. We found aspartyl protease activity for 100% of the isolates tested as well as variable DNAse, hemolysin, phospholipase and esterase activities. All strains had low MICs for amphotericin B and showed a variable response to fluconazole (0.125-32 µg/mL) and the echinocandins tested (0.25-> 8 µg/mL).
Related Concept Videos
Lytic Cycle of Bacteriophages
Yeast Signaling
Viral Replication: Lytic Cycle
Magnetic Susceptibility and Permeability
When diamagnetic materials are placed under an external magnetic field, the moments opposite to the field are induced. Hence, the susceptibility for diamagnets has a minimal negative value of 10-5–10-6. Since...
Susceptibility, Permittivity and Dielectric Constant
Co-activators and Co-repressors

