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Related Concept Videos

Schizophrenia01:17

Schizophrenia

843
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
843
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

539
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
539
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

503
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
503
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

512
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
512
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

524
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
524
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

591
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
591

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A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Schizophrenia Mortality: Barriers to Progress.

Mary V Seeman1

  • 1Department of Psychiatry, University of Toronto, 260 Heath St. West, Suite #605, Toronto, Ontario, M5P 3L6, Canada. mary.seeman@utoronto.ca.

The Psychiatric Quarterly
|June 1, 2019
PubMed
Summary
This summary is machine-generated.

People with schizophrenia face a 20-year shorter lifespan due to premature deaths. Addressing modifiable lifestyle, social, and purpose-in-life factors is crucial for improving longevity in this population.

Keywords:
AntipsychoticsCentariansMortalityPovertySchizophreniaStigmaStressSymptoms

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Area of Science:

  • Psychiatry
  • Gerontology
  • Public Health

Background:

  • Individuals with schizophrenia experience a significantly reduced lifespan, with natural causes accounting for the majority of premature deaths.
  • This mortality gap highlights a critical public health issue requiring investigation into factors influencing longevity.

Purpose of the Study:

  • To explore factors contributing to a long life, drawing parallels with centenarians, and examine their applicability to individuals with schizophrenia.
  • To identify barriers preventing the adoption of longevity-promoting factors in the schizophrenia population.

Main Methods:

  • A narrative review of literature published in the last decade.
  • Searches were conducted in PubMed and Google Scholar databases.

Main Results:

  • Four key factors associated with longevity in centenarians identified: genetics, healthy lifestyle behaviors, social support, and a subjective purpose in life.
  • While lifestyle, social support, and purpose are modifiable, significant barriers exist for individuals with schizophrenia, including poverty, illness symptoms, stress, stigma, and medication side effects.

Conclusions:

  • Addressing the identified barriers is essential to improve health outcomes and reduce mortality risk in people with schizophrenia.
  • Interventions aimed at enhancing lifestyle, social support, and life purpose must consider and mitigate these contextual challenges.