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IS THERE A RELATIONSHIP BETWEEN VITAMIN D STATUS AND HYPOCALCEMIA AFTER TOTAL THYROIDECTOMY?
G Dağlar1, M Ö Kiliç1, C Çelik1
1Numune Training and Research Hospital, Department of General Surgery, Ankara, Turkey.
Acta Endocrinologica (Bucharest, Romania : 2005)
|June 1, 2019
Summary
Low vitamin D levels significantly predict hypocalcemia after thyroidectomy. Severe vitamin D deficiency increases the risk of both biochemical and symptomatic hypocalcemia, suggesting supplementation can prevent complications.
Area of Science:
- Endocrinology
- Nutritional Science
- Surgical Outcomes
Background:
- Vitamin D is essential for calcium metabolism via parathormone.
- Vitamin D deficiency is linked to hypocalcemia post-thyroidectomy.
Purpose of the Study:
- To assess vitamin D's predictive role in post-thyroidectomy hypocalcemia.
- To investigate the association between preoperative vitamin D status and hypocalcemia.
Main Methods:
- Prospective study of 150 patients undergoing total thyroidectomy.
- Analysis of preoperative vitamin D levels and incidence of hypocalcemia.
- Comparison of hypocalcemia rates based on vitamin D status (<10 ng/mL vs. >10 ng/mL).
Main Results:
- Hypocalcemia occurred in 18.7% (biochemical) and 14.7% (symptomatic) of patients.
- Lower preoperative vitamin D levels were significantly associated with both biochemical and clinical hypocalcemia.
- Severe vitamin D deficiency (<10 ng/mL) markedly increased the risk of hypocalcemia.
Conclusions:
- Vitamin D deficiency, especially severe deficiency, is a significant risk factor for post-thyroidectomy hypocalcemia.
- While multifactorial, vitamin D status is a key predictor.
- Vitamin D supplementation may prevent hypocalcemia after thyroidectomy.
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