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OVARIAN GOITER AS A RARE CAUSE OF HYPERTHYROIDISM.

Z Frysak1, J Schovanek1, M Halenka1

  • 1Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc - Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Olomouc, Czech Republic.

Acta Endocrinologica (Bucharest, Romania : 2005)
|June 1, 2019
PubMed
Summary
This summary is machine-generated.

Ectopic ovarian thyroid tissue, though rare, can cause hyperthyroidism years after treatment for Graves disease. Surgical removal of the ovarian struma resolved the condition, highlighting the need for vigilant patient monitoring.

Keywords:
hyperthyroidismovarian goiterstruma ovariithyroidectomy

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Area of Science:

  • Endocrinology
  • Gynecologic Pathology
  • Surgical Case Reports

Background:

  • Ectopic thyroid tissue in the ovary is a rare cause of hyperthyroidism.
  • Diagnosis requires a high index of clinical suspicion and a multidisciplinary approach.
  • Functional ovarian struma is an uncommon entity.

Observation:

  • A patient with a history of Graves' disease and prior thyroidectomy with radioiodine ablation presented with recurrent hyperthyroidism ten years later.
  • Close clinical and laboratory follow-up was crucial in identifying the source of persistent thyroid hormone overproduction.
  • Laparoscopic adnexectomy was performed to remove the ectopic ovarian tissue.

Findings:

  • Histopathological examination confirmed a benign ovarian struma as the source of hyperthyroidism.
  • Surgical removal of the ovarian struma led to resolution of the hyperthyroid state.
  • This case underscores the potential for ectopic thyroid tissue to cause recurrent hyperthyroidism long after initial treatment.

Implications:

  • Patients treated for thyroid disease, particularly Graves' disease, may require long-term monitoring for atypical presentations of hyperthyroidism.
  • Clinicians must remain vigilant for unusual causes of persistent or recurrent hyperthyroidism, even after definitive treatment.
  • Ovarian struma should be considered in the differential diagnosis of hyperthyroidism in women, especially those with a history of thyroid surgery or ablation.