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ALZHEIMER'S DISEASE - ESTROGENS AND SELECTIVE ESTROGEN RECEPTOR MODULATORS, FRIENDS OR FOES?
L Coman1, H Păunescu2, R Catană3
1"Carol Davila" University of Medicine and Pharmacy, Faculty of Pharmacy, Dept. of Physiology, Bucharest, Romania.
Acta Endocrinologica (Bucharest, Romania : 2005)
|June 1, 2019
Summary
This study reviews how estrogens and SERMs impact inflammation in Alzheimer's disease (AD). Selective estrogen receptor therapies show promise for managing AD by influencing inflammation resolution.
Area of Science:
- Neuroscience
- Endocrinology
- Pharmacology
Background:
- Alzheimer's disease (AD) is the primary cause of dementia, marked by plaque and neurofibrillary pathology.
- Inflammation is a key factor in AD's pathophysiology.