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Related Concept Videos

Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

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The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
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Adrenal Gland Disorders01:27

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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
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Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

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Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
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Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla01:27

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The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
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Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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What is Cancer?02:12

What is Cancer?

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
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High-Throughput Dissociation and Orthotopic Implantation of Breast Cancer Patient-Derived Xenografts
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A CASE OF ADRENAL MYELOLIPOMA A PATIENT WITH BREAST CANCER.

H J Jeon1, S Y Lee2

  • 1Chunbguk National University, Dept. of Internal Medicine, Cheong-Ju, Republic of Korea.

Acta Endocrinologica (Bucharest, Romania : 2005)
|June 1, 2019
PubMed
Summary

Adrenal myelolipoma, a rare benign tumor, was incidentally discovered in a breast cancer patient. Surgical resection confirmed the diagnosis of this non-functioning adrenal mass.

Keywords:
adrenal Myelolipomaadrenal incidentalomabreast cancer

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Area of Science:

  • Endocrinology
  • Oncology
  • Radiology

Background:

  • Adrenal myelolipoma is a rare, benign tumor of adipose and hematopoietic tissue.
  • Often asymptomatic, adrenal myelolipomas are increasingly detected incidentally via abdominal imaging.
  • Coexistence with breast cancer is infrequently reported in medical literature.

Purpose of the Study:

  • To report a case of adrenal myelolipoma incidentally found during the presurgical evaluation of breast cancer.
  • To highlight the diagnostic process and management of a coexisting adrenal mass in a cancer patient.

Main Methods:

  • A 43-year-old woman with breast cancer underwent presurgical assessment for an adrenal mass.
  • Abdominal CT revealed a large, heterogeneous fatty mass in the right adrenal gland.
  • Comprehensive hormonal studies indicated a non-functioning adrenal mass, leading to surgical resection for definitive diagnosis.

Main Results:

  • Radiological findings suggested an adrenal mass with calcifications.
  • Hormonal assays (including DHEA-S, ACTH, cortisol, urine cortisol, metanephrine, and 17-ketosteroids) were within normal limits, indicating a non-functioning tumor.
  • Pathological examination confirmed the adrenal mass as a myelolipoma.

Conclusions:

  • Adrenal myelolipoma can coexist with breast cancer.
  • Incidental detection via imaging is common for adrenal myelolipoma.
  • Surgical resection is a viable treatment option for incidentally discovered adrenal myelolipomas, especially when malignancy needs to be excluded.