Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DOES GRAVES' DISEASE AFFECT ESOPHAGEAL MOTILITY?

Ö Karaman1, M İlhan1, S Turgut1

  • 1Bezmialem Vakif University, Endocrinology and Metabolism, Istanbul, Turkey.

Acta Endocrinologica (Bucharest, Romania : 2005)
|June 1, 2019
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drastic Impact of Donor Substituents on Xanthenes in the PDT of Glioblastoma.

JACS Au·2025
Same author

Novel preoperative computed tomography (CT)-derived parameters to enhance self-expanding metallic stents (SEMS) outcomes in obstructive colorectal cancer.

Clinical radiology·2025
Same author

Neutrophil Gelatinase-Related Lipocalin and Renal Resistive Index in the Diagnosis and Prognosis of Sepsis-Associated Acute Kidney Injury: A Cross-Sectional Study from Türkiye.

Nigerian journal of clinical practice·2025
Same author

Effect of Oral-Related Quality of Life and Sexual Function in Dentally Compromised Women: A Prospective Cohort Study.

Nigerian journal of clinical practice·2024
Same author

IN VIVO STUDY OF POTENTIAL MECHANISMS OF MACROPHAGE REPOLARIZATION ON THE BACKGROUND OF TUMOR GROWTH.

Experimental oncology·2024
Same author

EFFECT OF B. SUBTILIS ІМV B-7724 LECTIN ON THE ACTIVITY OF EFFECTORS OF CELLULAR ANTITUMOR IMMUNITY OF MICE WITH LEWIS LUNG CARCINOMA.

Experimental oncology·2024
Same journal

ANALYSIS OF SHORT-CHAIN FATTY ACIDS AND ASSOCIATION WITH GLUCAGON-LIKE PEPTIDE-1 IN HEALTHY, OBESE, PREDIABETES AND TYPE 2 DIABETES INDIVIDUALS.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
Same journal

ASSESSMENT OF NON-ENDOCRINOLOGIST PHYSICIANS' AWARENESS OF DIABETES TECHNOLOGIES: A NATIONWIDE SURVEY IN TURKEY.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
Same journal

LIPOHYPERTHROPHY: NEW TECHNOLOGY, OLD PROBLEMS.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
Same journal

EARLY REASSURANCE OR FALSE SAFETY? THE FETAL HOME DOPPLER USE IN ACTIVE MONITORING IN THE FIRST TRIMESTER OF PREGNANCY - FROM THE ENDOCRINE PERSPECTIVE.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
Same journal

LEVOTHYROXINE-SIMETHICONE DRUG INTERACTION AND PRESENCE OF MACRO-TSH IN AN INFANT WITH CONGENITAL HYPOTHYROIDISM.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
Same journal

DIAGNOSIS OF ACROMEGALY IN BILATERAL CARPAL TUNNEL SYNDROME AND FOLLOW-UP WITH ULTRASONOGRAPHY: A CASE REPORT.

Acta endocrinologica (Bucharest, Romania : 2005)·2026
See all related articles

Graves' disease, an autoimmune condition, can impact esophageal motility, leading to a shorter duration of contraction. This finding suggests gastrointestinal symptoms in hyperthyroid patients may stem from motility dysfunction.

Area of Science:

  • Gastroenterology
  • Endocrinology
  • Physiology

Background:

  • Hyperthyroidism, particularly Graves' disease, frequently affects the gastrointestinal system.
  • While gastrointestinal dysmotility is suspected in thyrotoxicosis, specific motility disorder research in hyperthyroidism is limited.

Discussion:

  • This study utilized esophageal manometry to assess motility in patients with Graves' disease.
  • A significantly shortened duration of esophageal contraction was observed in hyperthyroid patients compared to healthy controls.

Key Insights:

  • Esophageal motility is altered in Graves' disease, characterized by a reduced duration of contraction.
  • The duration of esophageal contraction negatively correlates with TSH receptor antibody titers.
  • The duration of esophageal relaxation shows a negative correlation with free thyroxine (fT4) levels.
Keywords:
Graves’ diseaseesophagusmanometrymotility

Related Experiment Videos

Outlook:

  • Esophageal motility dysfunction should be considered in the clinical evaluation of hyperthyroid patients.
  • Further research may elucidate the precise mechanisms linking thyroid hormones and esophageal function.