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Updated: Jan 24, 2026

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Published on: November 28, 2010
Concurrent high-grade serous carcinoma and borderline tumor demonstrating different chemo-sensitivity
Momoko Inoue1, Masataka Takenaka1, Masaharu Fukunaga2
1Department of Obstetrics and Gynecology, Jikei Daisan Hospital, 4-11-1 Izumi-Honchou, Komae-shi, Tokyo, 201-8601 Japan.
This study presents a rare case of concurrent ovarian high-grade serous adenocarcinoma and borderline tumor. The findings highlight differential chemo-sensitivity, with adenocarcinoma responding to chemotherapy while borderline tumor persisted.
Area of Science:
- Gynecologic Oncology
- Pathology
Background:
- Ovarian high-grade serous adenocarcinoma (HGSC) typically responds to platinum/taxane chemotherapy.
- Ovarian borderline tumors (OBT) often exhibit persistent disease despite treatment.
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