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Localized Cutaneous Hyalohyphomycosis by Fusarium spp. Over a Postsurgical Scar: Response to Fluconazole
Chetan D Rajput1, Sunil Lilani2, Kiran Paradeshi2
1Department of Skin and VD, SBH Govt. Medical College, Dhule, Maharashtra, India.
Abstract:
Hyalohyphomycosis are opportunistic fungal infections caused by fungi with colorless septate hyphae. Fusarium is a hyalohyphomycetes which can cause localized or disseminated infections depending on host immunity. Our patient had an infectious lesion over the coronary artery bypass grafting (CABG) scar which was not responding to antibacterial treatment. Further investigations revealed it to be localized cutaneous Fusarium infection. The patient was treated with fluconazole 3 mg/kg/day for 3 weeks and responded very well without any recurrence during the next 3 months follow-up. Thus, this case highlights the effectiveness of fluconazole in uncommon fungal infection.
Insights
This case study shows fluconazole effectively treated a rare cutaneous Fusarium infection on a coronary artery bypass grafting scar. The antifungal treatment led to complete recovery without recurrence, demonstrating its efficacy in similar fungal infections.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Hyalohyphomycosis are opportunistic infections caused by fungi with colorless septate hyphae.
- Fusarium species, a type of hyalohyphomycetes, can cause localized or disseminated infections based on host immunity.
Observation:
- A patient presented with an infectious lesion on a coronary artery bypass grafting (CABG) scar.
- The lesion was unresponsive to antibacterial therapy, prompting further investigation.
Findings:
- Investigations confirmed a localized cutaneous Fusarium infection.
- Treatment with fluconazole (3 mg/kg/day) for 3 weeks resulted in a complete resolution of the infection.
Implications:
- This case highlights fluconazole's effectiveness in treating uncommon cutaneous Fusarium infections.
- The findings suggest fluconazole as a viable treatment option for similar localized fungal infections, particularly in post-surgical scar sites.
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