Localized Cutaneous Hyalohyphomycosis by Fusarium spp. Over a Postsurgical Scar: Response to Fluconazole

Chetan D Rajput1, Sunil Lilani2, Kiran Paradeshi2

  • 1Department of Skin and VD, SBH Govt. Medical College, Dhule, Maharashtra, India.

Insights

This case study shows fluconazole effectively treated a rare cutaneous Fusarium infection on a coronary artery bypass grafting scar. The antifungal treatment led to complete recovery without recurrence, demonstrating its efficacy in similar fungal infections.

Area of Science:

  • Medical Mycology
  • Infectious Diseases

Background:

  • Hyalohyphomycosis are opportunistic infections caused by fungi with colorless septate hyphae.
  • Fusarium species, a type of hyalohyphomycetes, can cause localized or disseminated infections based on host immunity.

Observation:

  • A patient presented with an infectious lesion on a coronary artery bypass grafting (CABG) scar.
  • The lesion was unresponsive to antibacterial therapy, prompting further investigation.

Findings:

  • Investigations confirmed a localized cutaneous Fusarium infection.
  • Treatment with fluconazole (3 mg/kg/day) for 3 weeks resulted in a complete resolution of the infection.

Implications:

  • This case highlights fluconazole's effectiveness in treating uncommon cutaneous Fusarium infections.
  • The findings suggest fluconazole as a viable treatment option for similar localized fungal infections, particularly in post-surgical scar sites.

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