The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice

Da-Li Tong1, Rui-Guo Chen2, Yu-Lan Lu3

  • 1Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China; The College of Life Science, University of Chinese Academy of Sciences, Beijing, China.

Related Concept Videos

Social Scripts02:10

Social Scripts

People tend to know what behavior is expected of them in specific, familiar settings. A script is a person’s knowledge about the sequence of events expected in a specific setting (Schank & Abelson, 1977). Essentially, scripts are a particular kind of schema, one containing default values for the features within an event. In the restaurant example, the script's features include the props (e.g., tables, menu, food, and money), the roles to be played (e.g., customer and waiter),...
10.2K
Role of Emotions in Social Life01:01

Role of Emotions in Social Life

Emotions play a fundamental role in shaping human experience and interactions. The absence of emotions would render life incomplete and fail to capture the essence of human nature. In social psychology, feelings and moods have been extensively studied due to their profound impact on social life and interpersonal relationships. These affective states influence decision-making, behavior, and social perceptions, making them integral to understanding human interactions.Emotions and Social...
357
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
9.4K
Social Psychology and Individual Behavior01:29

Social Psychology and Individual Behavior

Social psychology examines how group dynamics, emotions, and cultural influences shape individual actions and decision-making. These elements interact to form behavioral patterns that affect personal choices and social interactions.The Role of Group DynamicsGroups play a crucial role in shaping behavior by reinforcing norms and expectations. Individuals derive a sense of self from group membership, often aligning their behaviors with group norms to maintain social cohesion. For example, an...
284
Causes of Social Behavior II: Cognitive Processes01:15

Causes of Social Behavior II: Cognitive Processes

Cognitive processes affect social behavior by guiding how individuals perceive, interpret, and respond to social stimuli. These mental processes enable individuals to assess others' behaviors, attribute causes to their actions, and form expectations based on past experiences.Causes of Behavior and Social JudgmentsIndividuals determine the causes of others' behaviors by distinguishing between personal traits and external circumstances. For example, if a friend frequently arrives late, an...
197
What is Behavior?00:54

What is Behavior?

Behaviors are actions that an organism engages in—they can be related to finding food, reproducing, defending against threats, and many other possible actions. Behaviors include activities related to the environment around the animal—such as migration—as well as social interactions within a species or population. Many behaviors involve motor output—that is, muscle movements—while others involve less visible actions, such as learning.
10.2K