Sex Hormone Receptor Signals in Human Malignancies

Hiroshi Miyamoto1,2,3

  • 1Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA. hiroshi_miyamoto@urmc.rochester.edu.

Insights

Sex steroids like androgens and estrogens impact many bodily functions beyond reproduction. They achieve this by interacting with sex hormone receptors, which are key regulators of gene activity.

Area of Science:

  • Endocrinology
  • Molecular Biology
  • Physiology

Background:

  • Sex steroids, encompassing androgens, estrogens, and progestogens, exert broad physiological effects.
  • These effects extend beyond the reproductive system.
  • They function through binding to sex hormone receptors, which are part of the nuclear receptor superfamily.

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