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Sex Hormone Receptor Signals in Human Malignancies
Hiroshi Miyamoto1,2,3
1Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA. hiroshi_miyamoto@urmc.rochester.edu.
Abstract:
Sex steroids, including androgens, estrogens, and progestogens, are known to have widespread physiological actions beyond the reproductive system via binding to the sex hormone receptors, members of the nuclear receptor superfamily that function as ligand-inducible transcription factors [...].
Insights
Sex steroids like androgens and estrogens impact many bodily functions beyond reproduction. They achieve this by interacting with sex hormone receptors, which are key regulators of gene activity.
Area of Science:
- Endocrinology
- Molecular Biology
- Physiology
Background:
- Sex steroids, encompassing androgens, estrogens, and progestogens, exert broad physiological effects.
- These effects extend beyond the reproductive system.
- They function through binding to sex hormone receptors, which are part of the nuclear receptor superfamily.
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