Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Experience with extracorporeal CO2 elimination].

M Knoch, E E Müller, W Höltermann

Der Anaesthesist

|May 1, 1987

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Detection of Mycoplasma hyopneumoniae by polymerase chain reaction in swine presenting respiratory problems.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2013

Same author

Determination of Neisseria gonorrhoeae susceptibility to ciprofloxacin in clinical specimens from men using a real-time PCR assay.

International journal of antimicrobial agents·2013

Same author

Anorexigenic postprandial responses of PYY and GLP1 to slow ice cream consumption: preservation in obese adolescents, but not in obese adults.

European journal of endocrinology·2012

Same author

Growth hormone variants: a potential avenue for a better diagnostic characterization of growth hormone deficiency in children.

Journal of endocrinological investigation·2012

Same author

GH and cortisol responses following an acute session of respiratory muscle endurance training in severely obese patients.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2012

Same author

GH responses to two consecutive bouts of respiratory muscle endurance training in healthy adults.

Journal of endocrinological investigation·2012

Extracorporeal CO2-elimination (ECCO2-R) effectively treated severe ARDS patients unresponsive to conventional ventilation. This method improved oxygenation and lung function, enabling ventilator weaning in most participants.

Area of Science:

Critical Care Medicine
Pulmonary Physiology
Respiratory Support

Context:

Severe Acute Respiratory Distress Syndrome (ARDS) presents a significant challenge in critical care.
Conventional mechanical ventilation often fails in severe ARDS cases.
Extracorporeal CO2-elimination (ECCO2-R) offers an alternative therapeutic strategy.

Purpose:

To evaluate the efficacy of ECCO2-R in patients with severe ARDS who failed conventional therapy.
To assess the impact of ECCO2-R on pulmonary function parameters, gas exchange, and lung fluid.

Summary:

Ten patients with severe ARDS received ECCO2-R using the Life-Support System (LSS) for 7-17 days.
Seven patients (Responders) showed satisfactory improvement, allowing ventilator weaning.

Related Experiment Videos

Three patients (Non-responders) had unchanged lung mechanics and gas exchange.

Responders exhibited improved oxygenation, decreased intrapulmonary shunt (Qs/Qt), reduced extravascular lung water, and normalized compliance and chest X-rays.

Impact:

ECCO2-R, combined with high PEEP and low-frequency ventilation, appears to be a promising method for treating acute pulmonary failure.
The study suggests potential for ECCO2-R to facilitate recovery and "cure" in severe ARDS.
This approach may offer a vital therapeutic option for patients with refractory respiratory failure.