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Updated: Jan 24, 2026

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
Published on: June 7, 2018
The role of lipoxin in regulating tumor immune microenvironments
Ting Zhang1, Hua Hao2, Xiao-Yan Zhou3
1Department of Pathophysiology, Medical College of Nanchang University, Nanchang 330006, China.
Abstract:
The tumor immune microenvironment is the living environment for cancer cells which is essential for supporting cancer cells. Vascular endothelial cells and fibroblasts play a vital role in tumor metastasis and angiogenesis, while macrophages, neutrophils, lymphocytes, and other immune cells play an important role in cancer progression. Lipoxin (LX) is a class of eicosanoids that can regulate components of the innate and adaptive immune system, including the above cells. This review summarizes the roles of LX in the regulation of tumor immune microenvironments in order to throw light on the application of LX in the clinical treatment of tumor immune microenvironments.
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