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Discovery of naphthacemycins as a novel class of PARP1 inhibitors

Wenbin Shen1, Xinhua Lu2, Jingtong Zhu1

  • 1New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijiazhuang 050015, Hebei, China.

Bioorganic & Medicinal Chemistry Letters
|June 3, 2019
PubMed

Keywords:
High-throughput screeningMicrobial metabolitesMolecular dockingNaphthacemycinsPARP1 inhibitor

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