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Tracking Spinal Cord Injury Functional Outcomes Across the Lifespan: Validation of Linking Coefficients
Pengsheng Ni1, M J Mulcahey2, Mary D Slavin1
1Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, MA.
Insights
Linking coefficients can transform Pediatric Spinal Cord Injury Activity Measure (PEDI-SCI/AM) scores to adult Spinal Cord Injury-Functional Index (SCI-FI) scores. These SCI-FI estimates are valid for specific domains, modes, and respondent types in pediatric SCI research.
Area of Science:
- Rehabilitation Medicine
- Pediatric Neurology
- Clinical Measurement
Background:
- Pediatric Spinal Cord Injury Activity Measure (PEDI-SCI/AM) and adult Spinal Cord Injury-Functional Index (SCI-FI) are crucial for assessing function.
- Transforming PEDI-SCI/AM scores to SCI-FI scores can facilitate longitudinal tracking and comparison across age groups.
- Validated methods are needed to ensure accurate score conversion in pediatric SCI populations.
Purpose of the Study:
- To validate linking coefficients for transforming Pediatric Spinal Cord Injury Activity Measure (PEDI-SCI/AM) scores to adult Spinal Cord Injury-Functional Index (SCI-FI) scores.
- To assess the accuracy and reliability of estimated SCI-FI scores derived from PEDI-SCI/AM data.
- To determine the influence of domain, respondent type, and administration mode on score transformation validity.
Main Methods:
- A cross-sectional study involving 107 children with SCI and 96 parents/caregivers.
- Administration of PEDI-SCI/AM and SCI-FI computerized adaptive tests (CATs) and short forms (SFs).
- Calculation of correlations between estimated SCI-FI (est-SCI-FI) and actual SCI-FI scores, with subsequent paired t tests and ICC analyses if linking criteria were met.
Main Results:
- Two domains (Daily Routine/Self-Care and General Mobility/Basic Mobility) met linking criteria for both parent and child respondents across CAT and SF modes.
- Linking criteria were met for wheelchair domains (child SF and CAT) and ambulation domains (child SF only).
- Excellent agreement (ICC range: 0.75-0.89) was observed, with most absolute score differences less than one standard deviation.
Conclusions:
- Linking coefficients can generate valid SCI-FI estimates from PEDI-SCI/AM scores.
- The validity of these estimates varies depending on the specific domain, administration mode (CAT vs. SF), and respondent type (child vs. parent).
- This method offers a valuable tool for consistent functional outcome measurement in pediatric SCI.
Objective:
Validation of linking coefficients to transform Pediatric Spinal Cord Injury Activity Measure (PEDI-SCI/AM) scores to adult Spinal Cord Injury-Functional Index (SCI-FI) scores.
Design:
This cross-sectional study administered PEDI-SCI/AM and SCI-FI computerized adaptive tests (CATs) and short forms (SFs) to children with SCI and parents or caregivers.
Setting:
Hospitals, university, and rehabilitation institute.
Participants:
About 107 children with SCI and 96 parent or caregivers.
Interventions:
Not applicable.
Main Outcome Measures:
Linking coefficients estimated SCI-FI (est-SCI-FI) scores from PEDI-SCI/AM scores for matched domains. Correlations between est-SCI-FI and actual SCI-FI scores were calculated. If correlations exceeded the criterion linking (0.866), the following analyses to compare est-SCI-FI and actual SCI-FI scores were conducted: paired t tests, intraclass correlation coefficients (ICCs 3, 1), percent of cases with absolute score differences at different thresholds.
Results:
Two matched domains, PEDI-SCI/AM Daily Routine/SCI-FI Self-Care and PEDI-SCI/AM General Mobility/SCI-FI Basic Mobility, met the linking criterion for both respondent-types (parent and child) and administration modes (CAT and SF). PEDI-SCI/AM Daily Routine and SCI-FI Fine Motor Function did not meet linking criterion for respondent type or mode. The linking criterion was met for wheelchair domains (child SF and CAT) and ambulation domains (child SF only). Significant differences between est-SCI-FI and actual SCI-FI scores were noted for all matched domains except Daily Routine/Self-Care (child SF only; parent SF and CAT). ICC values showed excellent agreement (range=0.75-0.89). Absolute differences between est-SCI-FI and actual SCI-FI scores were less than 1 standard deviation (except wheelchair CAT child).
Conclusions:
Linking coefficients applied to PEDI-SCI/AM scores can provide valid SCI-FI estimates that vary by domain, mode, and respondent type.
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