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Updated: Jan 24, 2026

Imaging the Aging Cochlea with Light-Sheet Fluorescence Microscopy
Published on: September 28, 2022
Effects of light on aging and longevity
1College of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, Hangzhou, 310018, China.
Abstract:
Increasing evidence suggests an important role for light in regulation of aging and longevity. UV radiation is a mutagen that can promote aging and decrease longevity. In contrast, NIR light has shown protective effects in animal disease models. In invertebrates, visible light can shorten or extend lifespan, depending on the intensity and wavelength composition. Visible light also impacts human health, including retina function, sleep, cancer and psychiatric disorders. Possible mechanisms of visible light include: controlling circadian rhythms, inducing oxidative stress, and acting through the retina to affect neuronal circuits and systems. Changes in artificial lighting (e.g., LEDs) may have implications for human health. It will be important to further explore the mechanisms of how light affects aging and longevity, and how light affects human health.
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