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Updated: Jan 24, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Identification and Management of Perioperative Anaphylaxis
Gerald W Volcheck1, David L Hepner2
1Division of Allergic Diseases, Department of Medicine, Mayo Medical School, Mayo Clinic, Rochester, Minn.
Abstract:
The authors present a case of a patient with multiple episodes of perioperative anaphylaxis. The incidence and the most common causes of perioperative anaphylaxis are reviewed. The most common causes can vary by country and the type of perioperative medications used. The unique environment and the multiple medications and substances used in the anesthesia and surgical setting that make a definitive diagnosis challenging are outlined. A systematic strategy to recognize the reaction, identify the culprit, and direct future management are demonstrated. Management of the patient experiencing perioperative anaphylaxis requires close collaboration between the anesthesia, surgical, and allergy teams.
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