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Published on: June 10, 2025
Pressure Injuries at Intensive Care Unit Admission as a Prognostic Indicator of Patient Outcomes
William T McGee1, Brian H Nathanson2, Elizabeth Lederman1
1William T. McGee is an intensivist in the Division of Critical Care, Department of Medicine, Baystate Medical Center, Springfield, Massachusetts; Brian H. Nathanson is Chief Executive Officer of OptiStatim, LLC, Longmeadow, Massachusetts; Elizabeth Lederman is APACHE data coordinator, Baystate Medical Center, Springfield, Massachusetts; Thomas L. Higgins is Chief Medical Officer at The Center for Case Management, Natick, Massachusetts, and Professor of Medicine at the University of Massachusetts School of Medicine-Baystate, Springfield, Massachusetts.
Patients admitted to the intensive care unit with pressure injuries experienced longer hospital stays. These injuries may indicate a higher risk of mortality, especially when other health scores are unavailable.
Area of Science:
- Critical care medicine
- Patient outcomes research
- Wound care
Background:
- Pressure injuries (pressure ulcers) are a significant complication for immobile patients.
- Early identification of pressure injuries upon intensive care unit (ICU) admission is crucial for effective treatment.
- The correlation between community-acquired pressure injuries and adverse outcomes in critically ill patients requires further investigation.
Purpose of the Study:
- To investigate if pressure injuries present at ICU admission predict longer hospital stays and increased mortality.
- To establish pressure injuries as a potential predictive marker for critical care outcomes.
Main Methods:
- Retrospective analysis of adult ICU admissions from 2010-2012 at a level I trauma center.
- Multivariable logistic regression and generalized linear models were used to assess the association between pressure injuries and outcomes.
- Analyses were adjusted for patient characteristics including age, comorbidities, and the Acute Physiology and Chronic Health Evaluation III score.
Main Results:
- Of 2723 patients, 180 (6.6%) had an admission pressure injury.
- Patients with pressure injuries had significantly longer unadjusted hospital stays (15.6 vs 10.5 days) and higher mortality (32.2% vs 18.3%).
- Multivariable analysis revealed pressure injuries were associated with a 3.1-day increase in length of stay; however, the association with mortality was not significant after adjusting for the APACHE III score.
Conclusions:
- Admission pressure injuries are an objective, easily identifiable factor linked to extended ICU stays.
- Pressure injuries may serve as a modest indicator of increased mortality risk, particularly when comprehensive scoring data is absent.
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