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Updated: Jan 24, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Sleep patterns and the risk of adverse birth outcomes among Chinese women
Bingqing Liu1, Lulu Song1, Lina Zhang1
1Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Objective:
To evaluate the association between sleep patterns (sleep duration or timing) in late pregnancy and adverse birth outcomes (preterm delivery or small for gestational age, SGA).
Methods:
An analysis of data from a prospective cohort study of pregnant women in Wuhan city, Hubei Province, China, between 2012 and 2014. Preterm delivery was defined as delivery before 37 gestational weeks. SGA was defined as neonatal birthweight below the 10th percentile of the predicted birthweight distribution.
Results:
In total, 11 192 women were included in the analysis. After adjustment for potential confounders, 9.1-10 hours of nocturnal sleep was associated with a lower likelihood of SGA (odds ratio [OR], 0.81; 95% confidence interval [CI], 0.66-0.99) as compared with 7.1-9 hours. As compared with intermediate mid-sleep time (between 02:46 and 04:00), early mid-sleep time (at or earlier than 02:45) was associated with a higher likelihood of preterm delivery (OR, 1.64; 95% CI, 1.28-2.10).
Conclusion:
Among a large cohort of pregnant Chinese women, 9.1-10 hours of nocturnal sleep was associated with a lower risk of SGA, whereas early mid-sleep time was associated with a higher risk of preterm delivery.
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